The recoded bacterium uses only 57 of the 64 possible genetic codes, freeing up seven to be used for different purposes ...

When the normal DNA sequence in an individual changes or mutates it can cause disease. The mutation may involve multiple genes and may be caused by environmental factors, or there may be ...

Scientists have rapidly developed technologies to edit DNA, including Cas9 nucleases and base editors, to treat genetic diseases. The study's researchers demonstrated how a "third-generation ...

The findings were published today in Nature Biomedical Engineering. Scientists have rapidly developed technologies to edit DNA, including Cas9 nucleases and base editors, to treat genetic diseases.

To date, people have encoded information into DNA the same way nature has, by linking the four nucleotide bases comprising DNA—A, T, C, and G—into a particular genetic sequence.

"Prime editing is a promising approach because, in theory, we can directly correct disease mutations to specific healthy DNA sequences of our choosing," said co-corresponding author Jonathan Yen ...