Study: A cell-based, spike protein binding assay highlights differences in antibody neutralising capacity for SARS-CoV-2 variants. Image Credit: Design_Cells / Shutterstock ...

These are antibodies that can bind to the virus in a way that they prevent the entry of the virus into the cell. Here we present a novel, high throughput neutralizing antibody test, the cPass™ ...

Readouts of the 50% and 80% neutralization titers in cell-based assays showed a high correlation with each other, as well as with the concentration of IgG antibodies against SARS-CoV-2 receptor ...

January 1, 2017 (Vol. 37, No. 1). The cell-based assay has become a mainstay of drug development, addressing new concerns raised by the advent of biologics. These concerns include the difficulties ...

Four tests for the detection of SARS-CoV-2 antibodies were developed and evaluated, as well as two tests for the detection of neutralizing antibodies. These tests, known as laboratory assays, are ...

Cell culture medium; 384-well assay plate (Corning #3712) Detection antibody (motavizumab, conjugated to AF-488), Figure 1; Methods. Day 1. Prepare serial dilutions of the neutralizing mAB in cell ...

Development and evaluation of four serological assays to detect SARS-CoV-2 antibodies and two assays to detect neutralizing antibodies Peer-Reviewed Publication Institut Pasteur ...

Binding of SARS-CoV-2 to the ACE2 receptor is crucial to its ability to infect our cells, and antibody design has been heavily targeted to the ACE2-binding region (the so-called receptor-binding ...

Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb), a global leader of life science research and clinical diagnostic products, announced the launch of the Bio-Plex™ Pro Human SARS-CoV-2 Variant ...

Scientists at the Ragon Institute of MGH, MIT and Harvard, publishing in the journal Cell, show that the potency of neutralizing antibodies which developed in COVID-19 patients was significantly ...