By experimentally capturing and imaging snapshots of protein synthesis of nascent chains on their ribosomes, the researchers have discovered the structural basis of how the thermodynamics of co ...

For example, it would broaden the range of proteins and nascent chain sequences that can be accommodated by Trigger factor; this may be required for Trigger factor to promiscuously associate with ...

Subsequently the SRP–ribosome–nascent chain complex migrates to the ER, where an interaction between SRP54 and a membrane-bound heterodimer called the ‘SRP receptor’ (SR) triggers release ...