Do they have any relation with binding affinity? How do we search for new instances of a motif in this sea of DNA? Sequence motifs are short, recurring patterns in DNA that are presumed to have a ...

A team of scientists has created a new guide to advance standards for collecting and cataloging DNA from marine species, ...

Coupling of these 'enrichment' approaches to high-throughput sequencing technologies promises to deliver a huge body of information about DNA sequence variation in populations and heralds a new ...

"A major use of transgenic mice has been to determine what DNA sequences regulate ... times in development," according to the National Center for Biotechnology. The definition, according to ...

These include the tendency for exogenous DNA sequences to undergo recombination, rearrangement and truncation before or during integration (but rarely after integration), the tendency for ...

Oligonucleotides are used as primers in polymerase chain reaction (PCR) to amplify specific DNA sequences. They are designed to be complementary to the target sequence and serve as starting points for ...

The Cas9 endonuclease is guided by a single guide RNA (sgRNA) to a specific DNA sequence, where it creates a double-strand break. This break can then be repaired through either non-homologous end ...

Using a simple genetic code to convert letters and numbers into three-base codons, Carter Bancroft and his team at the Mount Sinai School of Medicine (New York, NY) designed a DNA sequence ...

Atomic force microscope–based single-molecule force spectroscopy was employed to measure sequence-dependent mechanical properties of DNA by stretching individual DNA double strands attached ...

Debates on patenting DNA must evolve to reflect the global decline in filings and regional disparities in patenting activity. Our analysis identified a total of 15,603 patent families claiming ...

But in the case of highly degraded DNA samples extracted from processed food and feed, the abundance of longer target sequences will most probably be underestimated as a consequence of the ...