Mechanisms of antigen escape from BCMA- or GPRC5D-targeted immunotherapies in multiple myeloma. Nature Medicine, 2023; DOI: 10.1038/s41591-023-02491-5 ...

"When the drugs were applied, all the other cells died, but those with these mutations became survivors," Haertle explains. To prevent the tumor from becoming resistant through this mechanism, the ...

Drug resistance continues to be a major problem in proteasome inhibitor (PI) therapy for patients with multiple myeloma (MM). In a new review article, investigators outlined some of the latest ...