More information: Yanhe Zhao et al, Mouse radial spoke 3 is a metabolic and regulatory hub in cilia, Nature Structural & Molecular Biology (2025). DOI: 10.1038/s41594-025-01594-6 ...

The localization of the CEP290 protein in the ciliary transition zone was also affected in patients, so the variant in the RPGR gene could be related to an alteration in the trafficking and ...

The researchers' findings involving radial spoke 3 (RS3), reported in Nature Structural & Molecular Biology, help answer some fundamental questions about how motile cilia work and could eventually ...

Researchers have developed a new optical coherence tomography (OCT) approach that can directly image coordination of tiny hair-like structures known as motile cilia in their natural environment.

Oviductal motile cilia are essential for oocyte pickup but dispensable for sperm and embryo transport. Proceedings of the National Academy of Sciences, 2021; 118 (22): e2102940118 DOI: 10.1073 ...

Little is understood about how cilia, the tiny hairlike organelles that in humans are often the first lines of defense against pathogens in our lungs and respiratory tracks and even help push ...

Within this organizer, motile cilia beat rapidly to create a leftward directional flow of extracellular fluid, which is the first outward sign of a left-right difference.

Cilia—tiny hairlike protrusions found on certain cell types—come in three flavors. Motile cilia crowd the surface of specialized cells and move in harmony to generate liquid flow.

Moreover, the team noticed that the four different T2Rs localized to different parts of a single cilia. "As far as I know, no one has seen different receptors of the same family localizing ...

Top 7 From F1000 Top 7 From F1000 1. How cilia talk» Primary (non-motile) cilia use membrane proteins in their role as a coordinator of the cell’s signaling pathways. New findings show how a cilium ...

At a specific point during embryogenesis, motile cilia within this cluster move in unison to create a leftward directional flow of extracellular fluid, which is the first sign of the breaking of ...