Notably, monocyte precursors (in the bone marrow) can also directly respond to their environment, predetermining the basal state of individuals’ monocytes. The degree to which the functional ...

Amies, E., et al. (2024) Quiescent human blood monocyte states are pre-committed to an inflammatory synovial transcriptional program. Ann Rheum Dis. DOI: 10.1136/annrheumdis-2024-eular.5134.

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More information: Bone marrow derived monocytes give rise to self-renewing and fully differentiated Kupffer cells, Scott et., Nature Communications 2016 Yolk sac macrophages, fetal liver and adult ...

Monocytes Under conditions of atherosclerosis, monocytes are rapidly recruited into the vessel wall. Mouse monocytes develop from a bone marrow precursor cell, the monocyte-dendritic cell precursor ...

Importantly, injected monocytes contained negligible quantities of DC precursors or Ly6C − CD43 + monocytes (Fig EV2C). Temporal analysis showed that the phenotype of CD45.2 + monocyte‐derived cells ...

New work on the precursors of inflammatory synovial macrophages — The exact origin and precursor differentiation route of tissue macrophages remains controversial. At the 2024 congress of EULAR ...

Monocytes are innate immune cells that are formed in the bone marrow before being released into the blood (1). They differentiate in the circulation with three major monocyte subsets identified in ...

Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells. Nature Communications, 2016; 7: 10321 DOI: 10.1038/ncomms10321 ...