Ole Mortensen Lab Research One goal of our research is to enhance our understanding of how drugs of abuse, antidepressants, and other small molecules interact with and modulate the function of ...

It acts as “… the main transporter responsible for monoamine packaging in neurons,” the investigators noted. “We knew that VMAT2 is physiologically very important,” Lee said.

Monoamine transporters are a class of protein found in the cell membrane of neurons in the central and peripheral nervous system. They function as transporter protein of the neurotransmitters ...

Neurochemicals such as serotonin and dopamine play crucial roles in cognitive and emotional functions of our brain. Vesicular monoamine transporter 1 (VMAT1) is one of the genes responsible for ...

Monoamine neurotransmitters are involved in many neurological functions, and defects in their synthesis, metabolism and transport leads to a variety of disorders with subtly different clinical ...

Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal ...

Scientists at St. Jude Children’s Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal ...

Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons.

Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal ...