New model for replication of BKPyV virus, a major cause of kidney transplant failure Date: December 6, 2024 Source: University of Alabama at Birmingham Summary: BK polyomavirus, or BKPyV, is a ...

How Early Expression of TAg Drives Kidney Cell DNA Replication The prevailing model suggests that BKPyV expresses a protein called large tumor antigen, or TAg, early during infection.

News Release 6-Dec-2024 New model for replication of BKPyV virus, a major cause of kidney transplant failure There are no effective antivirals against BK polyomavirus in transplanted kidneys.

Researchers have shown unprecedented control of SIV replication and decay of viral reservoirs by combining a stringent model of infection with the interruption of antiretroviral therapy (ART). The ...

Telethon researchers revised previous models of prion structure and proposed a novel architecture consistent with recent experimental data. This new model allowed Pietro Faccioli's group to apply ...

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...