An electron-microscope analysis 7 of complex I from the mould Neurospora crassa revealed a bipartite structure, in which almost equally sized intra- and extramembrane parts form an L-shape.

It is localized in mitochondria, ... captured with a cryo-electron microscope. view more . Credit: ... and the energy released in this reaction is used to drive the proton pump.

Mitochondria are the powerhouses of our cells, generating energy that supports life. A giant molecular proton pump, called complex I, is crucial: It sets in motion a chain of reactions, creating a ...

Mitochondria are the powerhouses of our cells, generating energy that supports life. A giant molecular proton pump, called complex I, is crucial: It sets in motion a chain of reactions, creating a ...

For the first time, structural biologists have now visualized and analyzed the enzyme's atomic structure with the support of the institute's newly installed high-end cryo-electron microscope. Skip ...

Sodium and membrane potential. Scientists have known for some time that the proton gradient in mitochondria is narrow, owing to cellular buffering mechanisms that assure pH stabilization.

Mitochondria are the powerhouses of our cells, generating energy that supports life. A giant molecular proton pump, called complex I, is crucial: It sets in motion a chain of reactions, creating a ...