Researcher Alexander Mühleip, from Amunts lab, used the single-cell photosynthetic organism Euglena gracilis, which belongs to a phylum that also includes human parasites, to extract the mitochondrial ...

Journal: Proceedings of the National Academy of Sciences of the United States of America Published: 2023-12-19 DOI: 10.1073/pnas.2303713120 Affiliations: 4 Authors: 10 ...

The mitochondrial ATP synthase is energy-converting macromolecular machine that uses the electrochemical potential across the bioenergetic membrane called cristae. This potential is maintained via ...

Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth. Cell Reports, 2022; 38 (4): 110290 DOI: 10.1016/j.celrep.2021.110290 ...

Mechanistically, these muropeptides were shown to enter intestinal-cell mitochondria to interact with the F1 complex of ATP synthase, stabilizing the complex and increasing mitochondrial respiration.

The channel is a leak in the mitochondria known as the ATP synthase c-subunit ring [ACLC]. Channels are good drug targets because opening and closing them can drastically change the electrical ...

More information: Jiyao Song et al, The mitochondrial Hsp70 controls the assembly of the F1FO-ATP synthase, Nature Communications (2023). DOI: 10.1038/s41467-022-35720-5 ...

Mitochondrial ATP synthase is composed of dimers that, when come together, form membrane curvature that is essential for efficient energy conversion. While the mitochondrial signature lipid ...