The recombinant KIF3A/B complex (∼50-nm rod with two globular heads and a single globular tail) demonstrated plus end-directed microtubule sliding activity in vitro. In addition, we showed that KIF3B ...

This confirms that their role in the sliding of antiparallel microtubule bundles also occurs in anaphase cells, since the same has been shown in previous works only in vitro.

More information: Maksim Kalutskii et al, Microtubule dynamics are defined by conformations and stability of clustered protofilaments, Proceedings of the National Academy of Sciences (2025).

Motor protein dynamics and microtubule length regulation The motion of motor proteins on biopolymers is important for diverse biological processes. Actin, microtubules, and nucleic acids can serve as ...

Drugs that affect microtubule stability are currently under investigation as potential therapies for Alzheimer’s, because it is nearly universally accepted by the scientific community — evidenced by ...

Regulation of Microtubule Dynamics ... Acetylation detection: Immunocytochemistry of formaldehyde-fixed HeLa cells stained with anti-alpha tubulin (acetyl K40) antibody [EPR16772] (ab179484).

Visualizing 'unfurling' microtubule growth Date: November 13, 2018 Source: University of California - Davis Summary: Living cells depend absolutely on microtubules that form a scaffolding for ...

TACC's Frontera supercomputer helps model dynamical behavior of cell structural polymers called microtubules that could lead to better understanding neurodegenerative diseases.

Takashi Ishida, Yayoi Kaneko, Megumi Iwano, Takashi Hashimoto, Helical Microtubule Arrays in a Collection of Twisting Tubulin Mutants of Arabidopsis thaliana, Proceedings of the National Academy of ...