The cytokinesis-block micronucleus test (MNT), as a marker of chromosomal mutagen sensitivity, was applied in a number of studies enrolling breast cancer (BC) patients and subjects with known or ...

We have used the bone marrow micronucleus assay (BMMN) as a measure of clastogenicity, in response to etoposide exposure in murine bone marrow. Oral delivery of etoposide resulted in a reduced ...

The researchers employed OECD-validated testing strategies — bacterial reverse mutation (Ames test), chromosomal aberration, and micronucleus assays — to assess mutagenic, clastogenic, and ...