No. 10,000,772, which was issued in June 2018, and covers methods of using optimized guide RNA formats (including single-guide and dual-guide formats) in certain environments, including eukaryotic ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures.

RNA interference, as mentioned, is one mechanism of gene expression. How does it work? Broadly speaking, small snippets of RNA shut down protein synthesis by binding to, and interfering with, the ...

Shinji Honda, Ayumi Yokoyama, Nobuhiro Suzuki. RNA editing of genomic neighbors controls antiviral response in fungi. Cell Host & Microbe, 2025; 33 (4): 545 DOI: 10.1016/j.chom.2025.02.016 ...

In this study, researchers established an RNA codon expansion (RCE) platform to assign pseudouridine (Ψ)-modified RNA codons (ΨCodons: ΨGA, ΨAA, ΨAG) as novel "blank" codons for non-canonical ...