The Mayo Clinic diet is divided into two phases. "Lose It" is a two-week jump-start phase that emphasizes quick changes in habits, and we believe it is the healthiest way to lose weight quickly.

The Mayo Clinic Diet is a membership-based program — it costs $19.99 a month for 12 months — that uses a five-level food pyramid to guide people through the diet plan.

If you are unsure if your medications could have a problem with grapefruit, check with your pharmacist. Or check the Mayo Clinic's Web site for information on this topic.