The emerging role of SETD2 in regulating immune cell function is shedding light on potential therapeutic strategies for a ...

The emerging role of SETD2 in regulating immune cell function is shedding light on potential therapeutic strategies for a ...

The itching, redness and swelling of an allergic reaction are caused by mast cells—the vigilant first responders of the ...

Siglec-6 is a member of the family of cell surface receptors called Sialic acid-binding immunoglobulin-type lectins (Siglecs). Siglec-6 is expressed primarily on the surface of mature mast cells.

News provided by Allakos Inc. Feb 26, 2024, 7:02 AM ET – Atopic dermatitis and prurigo nodularis skin lesions show evidence of MRGPRX2 mast cell activation and activated macrophages ...

To grow, cancer tumors must hijack the immune system for their needs. One of the main tricks that most tumors use is to manipulate a type of immune cell called a macrophage, causing it to protect ...

--Allakos Inc., a biotechnology company developing AK006 for the treatment of mast cell-driven diseases, today announced positive results from the single and multiple ascending Phase 1 study of ...

Within six days, the cells differentiate, or transform, into alveolar macrophage-like cells. The generated cells are 94% genetically similar to human alveolar macrophages collected from lung washes.