Aberrant expression of CD2 and/or CD25 by bone marrow, peripheral blood or other extracutaneous tissue mast cells is currently used as a minor World Health Organization diagnostic criterion for ...

Mast cells develop from hematopoietic progenitors in response to stem-cell factor (KIT ligand), which is the ligand of the CD117 transmembrane tyrosine kinase receptor, encoded by KIT. CD117 ...

Thus, modern immunophenotyping technologies make it possible to use CD38 mast cells as an important marker of the tumor microenvironment and to identify new pathogenetically significant molecular ...

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into ...

Atopic dermatitis and prurigo nodularis skin lesions show evidence of MRGPRX2 mast cell activation and activated macrophages – – AK006 inhibited mast cell activation and reduced mast cell ...

Mast cells are tissue-resident immune cells that release histamine during allergic response. Mast Cell Activation Syndrome is a condition that very few people know about, sadly even most primary ...