The only other real mechanic of note here is Mandokir's focus, which isn't an issue if you're soloing him and only a minimal one if you're not. At 80, it's easiest to just ignore it entirely if ...

After Venoxis, you begin the trek towards the old spider-boss High Priestess Mar'li and Mandokir areas. Mar'li's area is closed off, and the only path now leads to a totally revamped Mandokir area.