Background: Pharmacogenomic testing to identify variations in genes that influence metabolism of antidepressant medications can enhance efficacy and reduce adverse effects of pharmacotherapy for major ...

In this review, we outline the mechanisms, safety and clinical evidence for neuromodulation in treatment-refractory major depression. The quality of evidence for the different neuromodulation ...

March 18, 2002 0 Question A 28-year-old patient presented at 12 weeks of pregnancy with symptoms of major depressive disorder. She was treated with amitriptyline 75 mg daily, and recovered well.

Depression is one of the leading contributors to disability worldwide. 1 It is estimated that more than 21 million adults in the U.S. experienced at least one major depressive episode in 2020 ...

News provided by NetraMark Holdings Inc. Feb 25, 2025, 08:00 ET ...

The company plans to recruit around 300 people with major depression for the phase 2 trial of DT-101, which is due to start this year, and to provide a first readout of clinical data in 2027.