Lab members found that as the expression of c-Myc increases in these cells, the protein attaches to the promoters and enhancers of all active genes, thereby amplifying the active genes’ transcription.

A new physiological salt-based method enables high-resolution transcription factor mapping in small and single-cell samples.

It's not the first to target the MYC protein, but research is still ongoing. "We are targeting dysregulated RNA polymerase I (Pol I) transcription in MYC-driven cancers," the company noted.

Study findings NT-B2R effectively suppressed MYC transcription activities and cell proliferation. Allyl and norbornene ester-building molecules were used to build the bicyclic scaffold.

By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene - a well-known cancer-causing gene ...

Publication shows that OGM can resolve translocation partners involving MYC in multiple myeloma (MM) more effectively than current methodsThe release of compelling data in MM underscores the ...

Company News Published 10/24/2024, 10:05 AM 0 Bionano Genomics' OGM outperforms in MYC gene study BNGO 0.00% ...

Myc proto-oncogene protein (MYC) is a transcription factor that can modulate the transcription of several genes, and its overexpression has been found in many cancer types, including hepatocellular ...

By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene -; a well-known cancer-causing gene ...

Bionano Announces Publication Outlining Utility of OGM for Resolution of MYC Gene Rearrangements in Multiple Myeloma Published Oct 24, 2024 8:00am EDT ...