MTHFR genes tell your body how to make the MTHFR protein, which you need to produce folate, a B vitamin. If you have an MTHFR gene mutation, your body may not break down folate as well as it should.

How does MTHFR affect pregnancy? A 2019 study examined 246 women who had experienced recurrent miscarriages and held the C677T MTHFR gene mutation.

Mutations can affect one (heterozygous) or both (homozygous) of these genes. There are two common types, or variants, of MTHFR mutations: C677T and A1298C. These gene mutations are relatively common.

Take the claim that MTHFR variants up a person’s risk of developing heart disease, for example: Some older research suggested that those with some amount of C677T variation may be at a higher ...

There are two common MTHFR gene variants: C677T and A1298C. For most individuals, the risk associated with these variants is so small that testing for them is not recommended ( here ).

Two well-characterized polymorphisms, MTHFR C677T (rs1801133) and MTHFR A1298C (rs1801131) have been reported in enzyme activity reduction. 9 In MTHFR C677T, transition from a C to a T nucleobase ...

The short answer is, MTHFR is something that’s vital to help detox the body and produce good health. As for the long answer, read on for a synopsis on why MTHFR is so important.

This interest in MTHFR can be traced right back to Reif’s 2008 paper, which linked a variant of the gene to “adverse events” after smallpox vaccines. It was a somewhat intriguing result then.

The short answer is, MTHFR is something that’s vital to help detox the body and produce good health. As for the long answer, read on for a synopsis on why MTHFR is so important.