"Interestingly, in cancer cells that are less susceptible to ferroptosis, lipid peroxidation occurred in the lysosomes, but this did not lead to lysosomal membrane damage," continues Yamada.

Cancer treatments necessarily target unchecked cell growth, and selectively kill cancer cells while sparing normal cells and avoiding general toxicity in the human body. To develop new treatments ...

“Interestingly, in cancer cells that are less susceptible to ferroptosis, lipid peroxidation occurred in the lysosomes, but this did not lead to lysosomal membrane damage,” continues Yamada. “Upon ...

Cancer treatments necessarily target unchecked cell growth, and selectively kill cancer cells while sparing normal cells and avoiding general toxicity in the human body. To develop new treatments ...

Lysosomes contain catabolic hydrolases that participate in the digestion of autophagic material (after fusion between lysosomes and autophagosomes), in acute cell death (after lysosomal-membrane ...

"Interestingly, in cancer cells that are less susceptible to ferroptosis, lipid peroxidation occurred in the lysosomes, but this did not lead to lysosomal membrane damage," continues Yamada.

An anticancer treatment technology that selectively targets cancer cell lysosomes and overcomes drug resistance has been developed by Professor Ja-Hyoung Ryu and his research team in the ...

Little organs within cells called lysosomes digest unwanted material. And like stomachs, they must be acidic to do so. If they aren't, cells stop growing. Researchers wanted to know why.

The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell ...

Little organs within cells called lysosomes digest unwanted material. And like stomachs, they must be acidic to do so. If they aren't, cells stop growing. Researchers wanted to know why.