In a mouse model, the nanoparticle, made of an FDA-approved polymer known ... a process called endocytotic trafficking and subsequently undergo a rapid endo-lysosome escape to the cytosol within the ...

In a recent study, scientists developed a novel technique to extract intact lysosomes from cells using magnetic nanoparticles. Their approach is much faster than previous methods and yields ...

Yet their long-term fate in cells remained unclear, even though it was generally accepted that gold nanoparticles remained intact indefinitely in the lysosome, the cell's "waste recycling centre." ...

In a recent study posted to the bioRxiv* preprint server, researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

However, only a handful of potential therapeutics can target lysosomes, and most of them lack cancer selectivity. Published in Nature Nanotechnology, this study shows that nanoparticles covered ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes.

Chinese scientists recently reported the key role of histone acetylation-regulated long noncoding RNA termed as lysosome cell ... significant cell death using nanoparticles (NPs)-mediated ...