Alphamab Oncology (stock code: 9966.HK) announced that the Investigational New Drug (IND) application for JSKN022, an independently developed innovative bispecific antibody-drug conjugate (ADC) ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications how the targeted suppression of lysosome function may lead to brain cancer therapy.

There is no cure for glioblastoma; treatments can slow cancer growth and reduce symptoms. Lysosome Lysosomes are organelles, enclosed by membranes, located within cells.

By detecting lipid oxidation, the research team found that lipid oxidation in lysosomes is the cause of ferroptosis, iron mediated cell death. This results to leakage of iron from lysosomes which ...

In a paper published in Nature Communications, researchers from Kyushu University, using cultured cells and mice, found that the lipid peroxidation of the lysosomes—the organelle responsible for ...

Lysosome Targeted Nanoparticle Aggregation Reverses Immunosuppressive Tumor Microenvironment for Cancer Immunotherapy Journal: Advanced Materials Published: 2024-11-01 DOI: 10.1002/adma.202412730 ...

DelveInsight’s Breast Cancer pipeline report depicts a robust space with 100+ Breast Cancer companies working to develop 120+ pipeline therapies for Breast Cancer treatment.

As such, they are also relevant for the development and growth of cancer. Hirao and colleagues first checked whether lysosome activity is an indicator of glioblastoma progression.