HHMI researchers solve a longstanding mystery about the origin of new cells in the liver. Howard Hughes Medical Institute (HHMI) scientists have identified stem cells in the liver that give rise to ...

Discover 8 ways mast cell activation syndrome causes widespread symptoms from digestive issues to brain fog, often mistaken ...

Hepatocytes, as the most abundant cell type in liver, are a potent source of fibrogenic lipid peroxides in inflammatory liver diseases. Platelets are a potent source of growth factors, and are ...

Researchers from Columbia University and the German Cancer Center have found that stellate cells—star-shaped liver cells long known as the main perpetrators of liver fibrosis—have a commanding ...

Mast cells are part of your immune system ... X-rays, ultrasounds, and CT scans may show problems such as bone loss or an enlarged liver, spleen, or lymph nodes. It helps to write down a list ...

including helping the liver clear toxic porphyrin buildup and reducing inflammation. It also decreased the presence of mast cells, a type of immune cell that produces histamine. For EPP patients ...

The ECM components in fibrotic liver are similar regardless of the underlying cause. Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells ...

ASM progresses quickly and involves the abnormal accumulation of mast cells in multiple organs, such as the liver, spleen, ...