The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

Liver TET1 was found to promote metabolic dysfunction-associated steatotic liver disease (MASLD) by regulating CD36 ...

The liver is a vital organ, crucial to digestion, metabolism and the elimination of toxins. It has a unique ability, ...

Researchers discovered a mechanism after acute liver damage occurs—and it could lead to treatments for those with severe liver problems.

New research identifies the liver protein PTPRD as a key regulator of metabolic liver disease. Reduced levels of PTPRD disrupt glucose and lipid metabolism, promote liver fat accumulation, and impair ...

Drug-induced liver injury (DILI) is a significant concern in clinical practice, arising from medications, herbs, and dietary ...

The liver uses cells called hepatocytes to accomplish many of these essential functions. These cells can be damaged by overexposure to toxins or fatigue. The body has an interesting way of protecting ...

The tool reduces pathologist variability in liver biopsy assessment during trials of treatments for metabolic ...

This type of liver cancer develops from the main liver cells called hepatocytes. It's more common in people with cirrhosis. Cirrhosis means scarring of the liver due to previous damage. For example, ...