Senescence of liver cells following acute severe liver disease - which can be caused by a number of diseases including viral infections or toxins such as paracetamol overdose - can cause ...

Liver transplants are the only option for many severe liver diseases, but there aren't enough donor livers available. This new method could provide an alternative by making cell therapy more ...

Aged mouse livers show enlarged hepatic zones and abnormal expression of bizonal liver cells. The immunofluorescent images depict liver sections stained for markers of zone 1 (red), zone 2/3 (blue ...

Hepatic stellate cells (HSCs) are activated to heal the liver when it has a lesion (such as fibrosis or fatty liver); their function is to protect the liver by producing an extracellular matrix ...

Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem cell-derived hepatic organoids, report researchers from Japan. These ...

HepaTx, a biotechnology company specializing in regenerative medicine, has entered into a license agreement with Mayo Clinic to advance HepaTx's innovative stem cell technology into clinical ...