Adult patients with metabolic dysfunction–associated steatohepatitis (MASH) and moderate or advanced liver fibrosis showed improved liver histology with a once-weekly dose of semaglutide (Wegovy ...

Kupffer cells are macrophages located in the liver that play a key role in liver pathology, concretely in metabolic dysfunction-associated steatotic liver disease (MASLD; formerly nonalcoholic fatty ...

Study to improve histology interpretation of cirrhotic liver biopsies highlights limitations of current histology techniques and re-emphasizes the clinical relevance and regulatory potential of ...

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis. MASH is a ...

Analysis of liver sinusoidal endothelial cells (“LSEC”) from screening and end of treatment biopsies in the Phase 2b NATIVE study showed evidence of LSEC capillarization in patients without ...

Further, improvement in liver fibrosis by at least one stage without worsening of MASH was reported among 30% vs. 14% in ITT and 41% vs. 18% in mITT and by at least two stages among 20% vs. 2% in ...

This work analyzes liver biopsy material from a phase 2 study sponsored by Galectin Therapeutics and explores how the use of a machine learning histology model could potentially improve the ...