The complement system, which consists of more than 30 plasma and cell-surface proteins, is activated by three pathways — the classical, lectin and alternative pathways — which lead to the ...

Deficiencies in the innate immunity lectin pathway of complement activation are implicated in a child’s vulnerability to infections in conditions such as cancer, but the role during critical ...

Omeros’ OMS721 is a human monoclonal antibody that inhibits MASP-2, which is the effector enzyme of the lectin pathway of the complement system. Omeros controls the worldwide rights to MASP-2 ...