We investigated lectin pathway cord blood concentrations in infants with neonatal sepsis. Study design: Case-control study including 47 infants with culture-proven neonatal sepsis and 94 matched ...
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Narsoplimab shows promise in reducing mortality for TA-TMA patientsNarsoplimab, also known as OMS721, is a monoclonal antibody targeting MASP-2, a key player in the lectin pathway of the complement system. The drug has received breakthrough therapy and orphan ...
Endothelial damage, which activates the lectin pathway of complement, plays a central role in the development of TA-TMA. The condition occurs in both autologous and allogeneic transplants but is ...
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