"Colossal compared the genomes of the dire wolf and the gray wolf, and from about 19,000 genes, they determined that 20 changes in 14 genes gave them a dire wolf," Rawlence said.

The dire wolf has come out of extinction — kind of By Katie Scott Global News Posted April 7, 2025 4:13 pm Updated April 8, 2025 12:53 pm ...

We got dire wolves, folks! That's right, the *not mythical* creatures portrayed in Game of Thrones once actually lived and thrived in Canada. A very large jaw bone from the extinct and prehistoric ...

Now, the dire wolf is back, brought bounding into the 21st century by Colossal Biosciences, a Dallas-based biotech company. On April 8, Colossal announced it had used both cloning and gene-editing ...

Just more than a week has gone by since Colossal Biosciences, the company seeking to bring back the woolly mammoth, revealed it had produced three live dire wolves puppies – Remus, Romulus and ...

For its dire wolf project, Colossal began with the aforementioned 13,000-year-old tooth from Ohio and 72,000-year-old inner ear bone from Idaho.

One thing that’s been overshadowed by the dire wolf hubbub is Colossal’s work with endangered red wolves (Canis rufus). In the 1970s, the U.S. Fish and Wildlife Service recognized that these ...

Ghost is one of the most legendary dire wolf characters in Game of Thrones. His story is sentimental and poignant as Jon Snow discovers an albino runt next to his mother’s body and makes it his own.

Now, Colossal’s own researchers have claimed to journalists that their research has again adjusted the picture, proposing that dire wolves arose from interbreeding between two different wolf ...

Correction: An earlier version of this story misstated when George R.R. Martin visited Colossal. It was in 2025. George R.R. Martin made fictional dire wolves integral to his books in the "A Song ...

SOUND ON. You’re hearing the first howl of a dire wolf in over 10,000 years. Meet Romulus and Remus—the world’s first de-extinct animals, born on October 1, 2024.

Roughly 13,000 years later, a U.S. company has taken a step aimed at bringing the dire wolf back from oblivion - aside from the TV versions in the popular "Game of Thrones" fantasy series.