C. William Balke, W. Gil Wier, Modulation of L-Type Calcium Channels by Sodium Ions, Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, No. 10 (May 15, 1992), pp ...

UNIVERSITY PARK, Pa. -- L-type calcium channel blockers (LCCBs) -- the most widely used drugs for treating hypertension -- may harm the heart as much as help it, according to a new study. The ...

When L-type calcium channels that are voltage-gated are activated by the depolarization of the myocyte membrane, they allow calcium ions from outside the cell to sweep into the cytoplasm.

Although one type of calcium channel, called the L-type, had been shown to control muscle contraction, the action of the other type, called the T-type, remained largely unknown, said Campbell.