Each chromosome pair viewed in a karyotype appears to have its own distinct "bar code" of bands. What changes do scientists look for in a karyotype when diagnosing diseases and disorders?

Photograph of a karyotype - the collection of chromosomes within each cell of an organism - from a male mouse engineered by Johns Hopkins Medicine researchers to model Down syndrome in a human.

What is the structure of a chromosome? Why does the total number of chromosomes in a cell matter? Learn how chromosomes self-organize within single cells, and how these patterns help us detect ...

In a recent study, scientists have developed a revolutionary chromosome identification system for alfalfa, one of the world's ...

2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that the marker is lacking ...