Stroke or cerebral ischemia is a leading cause of death and long-term disabilities worldwide. Although major advances have occurred in the past decades in the prevention of brain ischemia ...

But, this early study gives us reason to be somewhat optimistic: it follows years of research and hypotheses that such venom components and their ion channel-targets could be key to new stroke ...

Acid-sensing ion channels (ASICs) are proton-gated cation ... agents for the treatment of neurological disorders, such as stroke.

The image illustrates the structure of a potassium ion channel including the cytosolic domain (CTD), colored cyan, which is ...

Stroke is one of the leading causes of death ... bind to and activate a type of acidosis sensor called acid-sensing ion channels (ASICs), which are normally activated by acids.

Ion selectivity is an important property of cell membrane ion channels. For example, potassium ion channels are more permeable to potassium ions than to sodium ions. The mechanism underlying the ...

Ion channels are transmembrane proteins specifically involved with the transport of inorganic ions like Na+, K+, Ca2+, or Cl-. Ion channels are “gated”, i.e. they open in response to a ...

Pore-forming proteins in living cells, termed ion channels, are embedded in the outer membrane of almost all cell types and ...

In a new study, a team led by medical researchers at The Ohio State University has determined that these vesicles contain an ion channel—a protein that opens a corridor allowing electrical ...

View Full Profile. Learn about our Editorial Policies. The elusiveness of single ion channels intrigued researchers for another quarter of a century. In his youth, Erwin Neher, now a biophysicist at ...

In a world-first finding, they've identified a way to restore the faulty function of ion channels on immune cells using a well-known drug typically used for other medical purposes. The team had ...