Conditions along the small intestine differ completely from one point to another, from the crypts lining the inner walls to the tips of the protruding villi. While the area closest to the wall of ...

Migration Intestinal cells arise from stem cells that lie in indentations (i.e. the crypts) of the intestinal wall. These intestinal cells then migrate up the intestinal villi. During their migration, ...

These intestinal cells then migrate up the intestinal villi. During their migration, they perform a certain function, for example the absorption of nutrients or the production of hormones.

The human small intestine, though modest in diameter and folded compactly to fit into the abdomen, is anything but small. It measures on average about 20 feet from end to end and plays a big role in ...

The intestinal epithelium of our body consists of a myriad of elongated villi microarchitectures which increase the total surface area of the inner wall for better absorption of digested nutrients.

An increase in SGLT3a was responsible for about 45% of the villi growth triggered by reproduction, including cell expansion, but wasn't necessary for entire small intestine lengthening.

BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states. Cell Reports, 2022; 38 (9): 110438 DOI: 10.1016/j.celrep.2022.110438 ...

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes. That is what ...