The terms "intestinal barrier" and "intestinal permeability" describe two different aspects of the same anatomical structure, the intestinal wall composed of four layers, the mucosa, the submucosa ...

Now, researchers have determined that Western diets can also disrupt the crucial barrier in the gastrointestinal tract known as the gut mucosa. This disruption can raise an individual's risk of ...

Tea polyphenols can maintain the health of the intestinal mucosal barrier, preventing gut epithelial apoptosis, reducing intestinal mucosal damage and suppressing the inhibition of TLR2 ...

Maintaining the intestinal barrier is also essential for survival. Therefore, these two processes may be linked to one of the most important signalling pathways," summarises Wunderlich.

Recently, scientists at Insilico Medicine utilized the comprehensive generative chemistry engine Chemistry42 to discover a novel gut-restricted PHD inhibitor that shows promise for repairing the ...

A research review from 2022 also suggests vitamin D plays an important role in gut health, such as maintaining the intestinal mucosal barrier. Vitamin D deficiency may therefore lead to ...

Trained ILC3 responses promote intestinal defense. Science, 2022; 375 (6583): 859 DOI: 10.1126/science.aaz8777 ...

Organoid‐Based Human Stomach Micro‐Physiological System to Recapitulate the Dynamic Mucosal Defense Mechanism. Advanced Science, 2023; 10 (27) DOI: 10.1002/advs.202300164 ...