Conducted during his time at Washington University in St. Louis, the study found that these urea cycle defects lead to secondary impairment in the tricarboxylic acid (TCA) cycle, a key pathway for ...

His laboratory focuses on researching diseases including fatty liver disease, cardiovascular disease and Type 2 diabetes. "I'm excited to join the IU School of Medicine and the Wells Center," said ...

Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9th ...

Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism. Cell Metabolism, 2024; DOI: 10.1016/j.cmet.2024.07.007 ...