Early in the coronavirus disease 2019 (COVID-19) pandemic, it was clear that quick and accurate diagnostic techniques were required to deal with emerging infections and offset the negative impacts ...

The development of angiogenesis assays was a pivotal step in the discovery of proangiogenic and antiangiogenic molecules. Among them, in vitro assays have been quantitative and expeditious as ...

These days, scientists sometimes take a minimalist approach, throwing out the cell and its contaminating components altogether and keeping only what they need for transcription and translation. Such ...

"With proper and more predictive in vitro assays, the preclinical pipeline will become more efficient, faster, and economic. And importantly, animal experiments can be replaced or at least reduced." ...

See how researchers used DNA footprinting and gel shift assays to prove this ... on one end and then incubated in vitro both with and without the transcription factor of interest.

In vitro tube formation assays mimic blood vessel formation, but long turnaround times create drug testing bottlenecks. Download this technical note to explore how a qualitative, real-time, ...

5’CapQ assay procedure, with a time to result ... relative quantification without a standard as a function of in vitro transcription (IVT) or enzymatic capping optimization to maximize yield ...

COLOGNE, Germany--(BUSINESS WIRE)--The USPTO approved a patent for Axiogenesis AG for the invention of its in vitro assay to screen pharmaceutical drug candidates for effectiveness and safety in ...

Enzymes are a vital tool that make in vitro transcription possible and refine the reaction ... with over 2,000 scientific papers citing KASP assays. Key applications include validation and screening ...

we identified significant differences in the enzyme activity levels sought for different ADME-Tox assays,” said Philip Vorwald, vice president and general manager of Celsis In Vitro Technologies.

This has led to the development of an assay for quantitative analysis of teratomas (TeratoScore) as well as in vitro alternatives such as PluriTest and the hPSC Scorecard. We compared normal hPSCs, ...