Here we outline a protocol for the in vitro study of cell migration using a ring barrier–based assay. A 'barrier' is inserted in the culture chamber, which prevents cells from entering a defined ...

Cell migration is assayed in a true three-dimensional matrix that is more representative of the in vivo environment, and, because the assays are automatable, throughput sufficient for compound ...

Cell migration is a multistep process fundamental to essential physiological processes, including embryonic development and immune cell migration, in addition to pathological conditions, such as ...

This article explores the three main in vitro assays shedding light on MoAs and making reference to specific cases. T-cell activation was determined through the quantitation of cytokine secretion.

BMPER attenuated PI3K/AKT signaling and suppressed BMP4-driven smooth muscle activation in models of PAH. BMPER overexpression mitigated the vascular remodeling that characterizes pulmonary arterial ...

AMS Biotechnology has announced a new generation of novel two-dimensional cell-based assay kits developed for reproducibly screening test compounds that may stimulate or inhibit adherent cell ...