They found that CD28.ζ-CAR molecules shuttle through the immune synapse quickly, working within minutes to kill cancer cells. This enabled fast CAR T cell recovery and a mastery of “serial killing” of ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel ...

Journal Science Advances DOI 10.1126/sciadv.adq8114 Article Title Molecular dynamics at immune synapse lipid rafts influence the cytolytic behavior of CAR T cells Article Publication Date 10-Jan-2025 ...