The investigators designed the dose so that the area-under-the-curve concentration of serum immunoglobulin G (IgG) for the subcutaneous preparation would be equivalent to the intravenous preparation.

Interventions We used Privigen®, [21] a commercial preparation that is a high-purity 10% liquid IVIG stabilized by L-prolin. Privigen® retains the Fc and Fab functions of the immunoglobulin G ...

The first purified human immunoglobulin G (IgG) preparation used clinically was immune serum globulin (ISG), which was prepared in the 1940s by E. J. Cohn's group. It was originally formulated in ...

Topline data were announced from a phase 2/3 trial evaluating Flebogamma 5% DIF (immune globulin intravenous ) in patients with post-polio syndrome (PPS).

In patients with chronic lymphocytic leukemia (CLL), regular treatment with immunoglobulin replacement therapy was not ...

TEANECK, N.J., Dec. 5, 2023 /PRNewswire/ -- GC Biopharma USA announced that a manuscript describing its landmark CEX technology, which removes FXIa from its 10% intravenous immunoglobulin (IVIG ...

Fazekas et al. recently reported the results of a multinational, randomized, double-blind, placebo-controlled phase II trial of a new preparation of IVIg in 127 participants with RRMS.

Intravenous Immunoglobulin (IVIG) Significantly Reduces Respiratory Morbidity in COVID-19 Pneumonia: A Prospective Randomized Trial. medRxiv. 2. Dufort, E. M., Koumans, et al. (2020).

Intravenous immunoglobulin is used to treat many medical conditions, from chronic to acutely life-threatening, and its supply recently shifted abruptly and indefinitely, says Dr. Paul Biddinger ...

Treatment with IV immunoglobulin plus methylprednisolone resulted in a more favorable fever course — and fewer complications — in children with COVID-19-related multisystem inflammatory ...

AAIC: IV Immunoglobulin Stabilizes Alzheimer’s Symptoms Alzheimer's disease (AD) symptoms stabilize among patients treated with intravenous immunoglobulin (IVIG) for 36 months. (HealthDay News ...