The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and caloric intake, to regulate important pathways within the CNS controlling food intake.

Compared to sugar, consuming sucralose—a widely used sugar substitute—increases activity in the hypothalamus, a brain region ...

POMC and AgRP neurons in hypothalamus were widely known to regulate energy balance. Here, authors show that ARC CRABP1 neurons are identified as a new player influencing appetite and metabolism.

High-fat diet (HFD)-induced obesity is characterized by induction of inflammation in the hypothalamus ... in brain slices or quantitative real-time PCR in cell lines, was performed to determine ...