Important discrepancies are observed on the effectiveness and potency of gabapentin in acute nociception and sensitization due to inflammation and neuropathy. There is also some controversy in the ...

Hyperalgesia arising from sensitization of pain relays in the spinal dorsal horn shares many mechanistic and phenotypic parallels with memory formation. We discovered that mechanical hyperalgesia ...

Hyperpathia, hyperalgesia, and allodynia are three manifestations of central sensitization, a condition in which a higher than necessary degree of activity is triggered in the central nervous system.

Sensitization occurs when a nerve is damaged ... leading to nerve inflammation. Allodynia or hyperalgesia can result. Allodynia may happen when nerves carry pain messages incorrectly, possibly ...

A recent study found that nearly 1 in 10 people with multisite pain in a representative sample of Japan’s population met ...

The end result is a marked exaggeration of nociception, severe opioid tolerance, peripheral and central sensitization, and opioid-induced hyperalgesia. In Panel A, short-term opioid administration ...

Hyperalgesia is a condition where a person has an increased sensitivity and extreme response to pain. What may not hurt most people can cause severe pain in a person with hyperalgesia. Although ...

‌Hyperalgesia is when you have extreme sensitivity to pain. If you have this condition, your body overreacts to painful stimuli, making you feel increased pain. You can develop hyperalgesia if ...

such as hyperalgesia and sensitization, and the signs to assess the stun quality and death to comprehend the relevance of a proper technique according to the species.

The aim of the present study was to investigate the influence of the spinal cord sensitization on the antinociceptive activity of gabapentin in the absence and in the presence of monoarthritis or ...