Excessive alcohol consumption causes alcoholic liver disease, and about 20% of these cases progress to alcohol-associated steatohepatitis (ASH), which can lead to liver cirrhosis and liver failure.

Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and aging are locked in a vicious circle: ...

Excessive alcohol consumption causes alcoholic liver disease, and about 20% of these cases progress to alcohol-associated steatohepatitis (ASH), which can lead to liver cirrhosis and liver failure.

Liver health is crucial for overall well-being, as this unique organ performs over 500 vital functions, including ...

Chronic liver disease (CLD) is a major global health concern, affecting approximately 1.5 billion people. This ...

Using single-cell RNA sequencing of murine macrophages, a distinct and highly susceptible Kupffer cell subtype, Clec4F + /CD206 +, emerged, with heme oxygenase 1 (HMOX-1) playing a pivotal role.

In the short term, these multi-zonal liver organoids will help scientists shed new light on diseases including diabetes, drug-induced liver injury, alcohol-related liver disease, and viral hepatitis.