It’s among the smallest of human chromosomes, but the complex structure of the Y chromosome has made it notoriously resistant to efforts to fully decipher it. Now, the first-ever complete ...

For decades, the Y chromosome — one of the two human sex chromosomes — has been notoriously challenging for the genomics community to sequence due to the complexity of its structure. Now, this elusive ...

While all human chromosomes contain repeats, more than 30 million letters of the Y chromosome — out of 62.5 million — are repetitive sequences, sometimes called satellite DNA or junk DNA.

Since chromosomes are millions of base pairs long, it was thought that this would inevitably destroy their structure, as many of the fragments would simply diffuse away.

Unlocking the full sequence of the human Y chromosome represents a breakthrough in genetics, presenting fresh opportunities for studying digestive disorders as per a study published in the journal ...

More information: Zhiyu Cao et al, Motorized chain models of the ideal chromosome, Proceedings of the National Academy of Sciences (2024). DOI: 10.1073/pnas.2407077121 Provided by Rice University ...

The Y chromosome is unusually repetitive, making it particularly difficult to sequence and assemble; it contains a complex repeat structure that includes long palindromes, tandem repeats, and ...

While all human chromosomes contain repeats, about 30 million letters of the Y chromosome are repetitive sequences. It's as if the same few sentences were repeated for half the length of the book.

This complete Y chromosome has 106 protein-coding genes, which is 41 more than in the reference genome. But almost all these extra genes are just copies of one gene called TSPY. At the same time ...

For decades, the Y chromosome – one of the two human sex chromosomes – has been notoriously challenging for the genomics community to sequence due to the complexity of its structure.