After experiencing a major downturn in his condition Saturday that required high oxygen treatment and blood transfusions, Pope Francis is resting as faithful and church leaders in Rome and across the world rally in prayer.

Pope Francis remains in critical condition and “is not out of danger,” the Holy See Press Office announced Saturday evening in Rome. The 88-year-old pontiff “experienced an asthma-like respiratory crisis of prolonged intensity” Saturday morning that required the administration of high-flow oxygen, according to the Vatican’s medical update.