To determine the structure of the HIV protein coat (also know as the capsid), the researchers ran simulations at the petascale level using the Blue Waters supercomputer at the University of Illinois.

Knowing the structure of the molecule you’re targeting helps you find or make a drug that will fit.” Knowledge of HIV Pol’s structure sheds new light on how HIV reproduces itself.

A new technique using electron tomography and subtomogram averaging at Diamond’s electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host ...

The authors said the discovery opens the door for important follow-up research, including studies of the HIV Pol structure of the larger and more complex polyprotein Gag-Pol, also involved in ...

They reveal the crystal structure of the virus surface protein gp120 from the simian immunodeficiency virus, which is closely related to HIV.

As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there’s a spectacularly brief moment in which a tiny piece of its surface snaps open to ...

HIV up close: Unprecedented view of virus reveals essential steps for causing AIDS Date: October 9, 2020 Source: University of Utah Health Summary: Accomplishing a feat that had been a pipe dream ...

Human immunodeficiency virus type 1 (HIV-1) has remained one of the most formidable challenges to human health since the first reported case in 1981, causing over 42 million deaths in total and ...

HIV PROTEIN ‘MISREPRESENTED’ The prospective vaccine only contained an HIV protein, not the virus itself, a spokesperson for CSL told Reuters for a previous fact-check.

Scientists use pore-forming toxin to punch holes in the membrane of HIV virus-like particles, making the capsid accessible to external cell factors and small molecules.