Research from an international team finds that the human gut is a site of rapid change, with recent and important deviations ...

Technical Terms Paneth cells: Specialised epithelial cells located at the base of the intestinal crypts, responsible for secreting antimicrobial peptides that contribute to mucosal defence.

Gut support cells communicate with surprising precision – like brain neurons – using tiny extensions to send instructions to ...

Intestinal epithelial cells line the inner wall of the gut, creating a barrier against dangerous bacteria like enteropathogenic E. coli that seek to attach to and destroy this barrier. Such pathogens ...

Scientists are also studying how the immune system deals with this microbiome, and learns to tolerate it. The human body has to sequester the gut microbiome, and the gut lining or epithelium is a ...

Researchers have discovered a novel gut-brain sensory circuit in mice where specialized colonic cells sense bacterial flagellin and rapidly suppress feeding via the vagus nerve. This "neurobiotic ...

The intestinal epithelium exhibits the highest cell turnover rate in the adult body, requiring constant and precise regulation of intestinal stem cells (ISCs) to sustain the production of new ...

Epithelial cells form the skin’s outer layer and line the gut, blood vessels, airways—basically “every single organ in your body that connects to the outside world,” says Ellen Foxman, who ...

For this research, the Magness lab focused on the epithelium: the single-cell thick layer separating the inside of the intestines and colon from everything else. Like other cell populations and the ...