Scientists at ORNL then attached the ribozyme pieces to guide RNA sequences designed to bind to a specific RNA target inside ...

use RNA to guide them to specific sites on DNA. TIGR systems can be reprogrammed to target any DNA sequence of interest, and ...

They also built a machine learning model to predict how well a guide RNA will perform for a set of target sequences, saving future users the headache of multiple trials. In its unaltered state, the ...

But to date this technology -- which allows scientists to use a 'guide' RNA to modify DNA sequences and evaluate the effects -- is able to target, delete, replace, or modify only single gene ...

This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it in its search. When the CRISPR Cas9 protein is added to ...

Researchers have developed a simple and cost-effective blood test capable of detecting Parkinson's disease long before ...

Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny ...

Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering clues for future RNA ...

First, a DNA sequence is designed in a computer-assisted process. It codes for the shape that the RNA should assume after folding. To approximate the desired structure, suitable RNA motifs must be ...

Scientists at ORNL then attached the ribozyme pieces to guide RNA sequences designed to bind to a specific RNA target inside the plant cell. When the guide RNA finds its target, the two ribozyme ...