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Scientists at ORNL then attached the ribozyme pieces to guide RNA sequences designed to bind to a specific RNA target inside the plant cell. When the guide RNA finds its target, the two ribozyme ...
use RNA to guide them to specific sites on DNA. TIGR systems can be reprogrammed to target any DNA sequence of interest, and ...
They also built a machine learning model to predict how well a guide RNA will perform for a set of target sequences, saving future users the headache of multiple trials. In its unaltered state, the ...
This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it in its search. When the CRISPR Cas9 protein is added to ...
is a new take on these RNA-imaging tools based on naturally occurring RNA sequences, called riboswitches, that fold robustly in the cellular environment and bind their ligands tightly and specifically ...
A guide RNA, along with the addition of an oligonucleotide sequence, sent the Cas9 RNA-ward. “Just as CRISPR-Cas9 is making genetic engineering accessible to any scientist with access to basic ...
Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering clues for future RNA ...
Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny ...
Researchers have developed a simple and cost-effective blood test capable of detecting Parkinson's disease long before symptoms emerge, comparing the current state of diagnosing neurodegenerative ...
Scientists at ORNL then attached the ribozyme pieces to guide RNA sequences designed to bind to a specific RNA target inside the plant cell. When the guide RNA finds its target, the two ribozyme ...